As of 1st of December Ronnie Berntsson has started as a Wallenberg Molecular Medicine Fellow at Umeå University.
This paper from the Wolf-Watz lab describes the discovery of a fundamentally new mechanism underlying protein-protein interactions. The chaperone-binding domain of the Yersinia effector protein YopH was found to lose its globular structure upon formation of a wrap-around architecture with its chaperone SycH. The mechanism is best described as a coupled binding and disordering event. The finding was enabled by an integrated structural biology approach by a five-lab effort and centered on NMR, SAXS and computational chemistry.
The article is published in Journal of Molecular Biology (2018), 430, 3157.
On June 1st Artur Dingeldein successfully defended his PhD thesis.
Zhang J, Grundström C, Brännström K, Iakovleva I, Lindberg M, Olofsson A, Andersson PL, Sauer-Eriksson AE.
Environ Sci Technol. 2018, 52, 11865-11874.
Kulén M, Lindgren M, Hansen S, Cairns AG, Grundström C, Begum A, van der Lingen I, Brännström K, Hall M, Sauer UH, Johansson J, Sauer-Eriksson AE, Almqvist F. J Med Chem. 2018 May 10;61(9):4165-4175.
The Berntsson group just published a new article titled “PrgB Promotes Aggregation, Biofilm Formation, and Conjugation through DNA Binding and Compaction”, with the first author Dr. Andreas Schmitt. Check it out here at Molecular Microbiology.
Practical Course on Rapid Cloning, Protein Expression, and Purification
CPEP 18 – 3 ECTS, 28th February – 9th March 2018
- The deadline is extended until 16 February
- The course is Free of Charge the fee has been cancelled
(acceptance is on a first come first serve basis)
Max number of participants 12.
More information on our course website here:
Contact and course organiser: Uwe.Sauer@umu.se, Protein Expertise Platform at Umeå University (PEP)
On February 5th Roland Locmelis successfully defended his PhD thesis.
Titel: “Structural biology studies of thylacoid lumen proteins required for photosystem II assembly and function”
Date: 5th of February
Place: N430, Naturvetarhuset UmU
Supervisor: Uwe H. Sauer