New publication in PNAS describing the tripartite cytotoxin MakABE from V. cholerae

In this paper the crystal structures of MakA, MakB and MakE are characterized. They are proteins that are secreted via the bacterial flagellum. Together they form a tripartite toxin that lyses erythrocytes and is cytotoxic to cultured human cells. The work was lead by group Karina Persson.

https://doi.org/10.1073/pnas.2111418118